Properties of a Novel GABAA Receptor γ2 Subunit Mutation Associated With Seizures
We recently identified a novel missense mutation of the γ2 subunit at position 40 with serine (N40S) of the GABAA receptor from a patient with epilepsy. Here, we report properties of the mutant receptor using the whole cell patch clamp technique. The Hill coefficient for the N40S receptor was greate...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2013-01-01
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| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319304074 |