Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes

Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.

Bibliographic Details
Main Authors: Noa Katz, Eitamar Tripto, Naor Granik, Sarah Goldberg, Orna Atar, Zohar Yakhini, Yaron Orenstein, Roee Amit
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21578-6