Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes
Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21578-6 |
| _version_ | 1818752644517199872 |
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| author | Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit |
| author_facet | Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit |
| author_sort | Noa Katz |
| collection | DOAJ |
| description | Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores. |
| first_indexed | 2024-12-18T04:54:44Z |
| format | Article |
| id | doaj.art-9616667022114a1680b5c585955aa3b8 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:54:44Z |
| publishDate | 2021-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9616667022114a1680b5c585955aa3b82022-12-21T21:20:19ZengNature PortfolioNature Communications2041-17232021-03-0112111510.1038/s41467-021-21578-6Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettesNoa Katz0Eitamar Tripto1Naor Granik2Sarah Goldberg3Orna Atar4Zohar Yakhini5Yaron Orenstein6Roee Amit7Department of Biotechnology and Food Engineering, Technion - Israel Institute of TechnologyDepartment of Biomedical Engineering, Ben-Gurion University of the NegevDepartment of Biotechnology and Food Engineering, Technion - Israel Institute of TechnologyDepartment of Biotechnology and Food Engineering, Technion - Israel Institute of TechnologyDepartment of Biotechnology and Food Engineering, Technion - Israel Institute of TechnologyDepartment of Computer Science, Technion - Israel Institute of TechnologySchool of Electrical and Computer Engineering, Ben-Gurion University of the NegevDepartment of Biotechnology and Food Engineering, Technion - Israel Institute of TechnologyPhage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.https://doi.org/10.1038/s41467-021-21578-6 |
| spellingShingle | Noa Katz Eitamar Tripto Naor Granik Sarah Goldberg Orna Atar Zohar Yakhini Yaron Orenstein Roee Amit Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes Nature Communications |
| title | Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes |
| title_full | Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes |
| title_fullStr | Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes |
| title_full_unstemmed | Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes |
| title_short | Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes |
| title_sort | overcoming the design build test bottleneck for synthesis of nonrepetitive protein rna cassettes |
| url | https://doi.org/10.1038/s41467-021-21578-6 |
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