Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Abstract The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches are limited to preventing progression of the disease. Recent studies have shown that exosomes play a vital role in cell-to-cell communication, and pathogenesis of many age-related diseases. Molecular pr...

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Bibliographic Details
Main Authors: Ravindra Kolhe, Monte Hunter, Siyang Liu, Ravirajsinh N. Jadeja, Chetan Pundkar, Ashis K. Mondal, Bharati Mendhe, Michelle Drewry, Mumtaz V. Rojiani, Yutao Liu, Carlos M. Isales, Robert E. Guldberg, Mark W. Hamrick, Sadanand Fulzele
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01905-y