Stiff Substrates Enhance Endothelial Oxidative Stress in Response to Protein Kinase C Activation

Arterial stiffness, which increases with aging and hypertension, is an independent cardiovascular risk factor. While stiffer substrates are known to affect single endothelial cell morphology and migration, the effect of substrate stiffness on endothelial monolayer function is less understood. The ob...

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Bibliographic Details
Main Authors: Rebecca Lownes Urbano, Swathi Swaminathan, Alisa Morss Clyne
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2019/6578492