Plasmonic Gold Nanoisland Film for Bacterial Theranostics
Plasmonic nanomaterials have been intensively explored for applications in biomedical detection and therapy for human sustainability. Herein, plasmonic gold nanoisland (NI) film (AuNIF) was fabricated onto a glass substrate by a facile seed-mediated growth approach. The structure of the tortuous gol...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/11/11/3139 |
| _version_ | 1827675811665149952 |
|---|---|
| author | Shih-Hua Tan Sibidou Yougbaré Hsuan-Ya Tao Che-Chang Chang Tsung-Rong Kuo |
| author_facet | Shih-Hua Tan Sibidou Yougbaré Hsuan-Ya Tao Che-Chang Chang Tsung-Rong Kuo |
| author_sort | Shih-Hua Tan |
| collection | DOAJ |
| description | Plasmonic nanomaterials have been intensively explored for applications in biomedical detection and therapy for human sustainability. Herein, plasmonic gold nanoisland (NI) film (AuNIF) was fabricated onto a glass substrate by a facile seed-mediated growth approach. The structure of the tortuous gold NIs of the AuNIF was demonstrated by scanning electron microscopy and energy-dispersive X-ray spectroscopy. Based on the ultraviolet-visible spectrum, the AuNIF revealed plasmonic absorption with maximum intensity at 624 nm. With the change to the surface topography created by the NIs, the capture efficiency of <i>Escherichia coli</i> (<i>E. coli</i>) by the AuNIF was significantly increased compared to that of the glass substrate. The AuNIF was applied as a surface-enhanced Raman scattering (SERS) substrate to enhance the Raman signal of <i>E. coli</i>. Moreover, the plasmonic AuNIF exhibited a superior photothermal effect under irradiation with simulated AM1.5 sunlight. For photothermal therapy, the AuNIF also displayed outstanding efficiency in the photothermal killing of <i>E. coli</i>. Using a combination of SERS detection and photothermal therapy, the AuNIF could be a promising platform for bacterial theranostics. |
| first_indexed | 2024-03-10T05:12:03Z |
| format | Article |
| id | doaj.art-961b70d0303a45f2ace1e6111c999357 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T05:12:03Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-961b70d0303a45f2ace1e6111c9993572023-11-23T00:43:46ZengMDPI AGNanomaterials2079-49912021-11-011111313910.3390/nano11113139Plasmonic Gold Nanoisland Film for Bacterial TheranosticsShih-Hua Tan0Sibidou Yougbaré1Hsuan-Ya Tao2Che-Chang Chang3Tsung-Rong Kuo4Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, TaiwanInstitut de Recherche en Sciences de la Santé (IRSS-DRCO)/Nanoro, 03 B.P 7192, Ouagadougou 03, Burkina FasoSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, TaiwanThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, TaiwanGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, TaiwanPlasmonic nanomaterials have been intensively explored for applications in biomedical detection and therapy for human sustainability. Herein, plasmonic gold nanoisland (NI) film (AuNIF) was fabricated onto a glass substrate by a facile seed-mediated growth approach. The structure of the tortuous gold NIs of the AuNIF was demonstrated by scanning electron microscopy and energy-dispersive X-ray spectroscopy. Based on the ultraviolet-visible spectrum, the AuNIF revealed plasmonic absorption with maximum intensity at 624 nm. With the change to the surface topography created by the NIs, the capture efficiency of <i>Escherichia coli</i> (<i>E. coli</i>) by the AuNIF was significantly increased compared to that of the glass substrate. The AuNIF was applied as a surface-enhanced Raman scattering (SERS) substrate to enhance the Raman signal of <i>E. coli</i>. Moreover, the plasmonic AuNIF exhibited a superior photothermal effect under irradiation with simulated AM1.5 sunlight. For photothermal therapy, the AuNIF also displayed outstanding efficiency in the photothermal killing of <i>E. coli</i>. Using a combination of SERS detection and photothermal therapy, the AuNIF could be a promising platform for bacterial theranostics.https://www.mdpi.com/2079-4991/11/11/3139gold nanoisland filmsurface-enhanced Raman scatteringdetectionphotothermal therapytheranostics |
| spellingShingle | Shih-Hua Tan Sibidou Yougbaré Hsuan-Ya Tao Che-Chang Chang Tsung-Rong Kuo Plasmonic Gold Nanoisland Film for Bacterial Theranostics Nanomaterials gold nanoisland film surface-enhanced Raman scattering detection photothermal therapy theranostics |
| title | Plasmonic Gold Nanoisland Film for Bacterial Theranostics |
| title_full | Plasmonic Gold Nanoisland Film for Bacterial Theranostics |
| title_fullStr | Plasmonic Gold Nanoisland Film for Bacterial Theranostics |
| title_full_unstemmed | Plasmonic Gold Nanoisland Film for Bacterial Theranostics |
| title_short | Plasmonic Gold Nanoisland Film for Bacterial Theranostics |
| title_sort | plasmonic gold nanoisland film for bacterial theranostics |
| topic | gold nanoisland film surface-enhanced Raman scattering detection photothermal therapy theranostics |
| url | https://www.mdpi.com/2079-4991/11/11/3139 |
| work_keys_str_mv | AT shihhuatan plasmonicgoldnanoislandfilmforbacterialtheranostics AT sibidouyougbare plasmonicgoldnanoislandfilmforbacterialtheranostics AT hsuanyatao plasmonicgoldnanoislandfilmforbacterialtheranostics AT chechangchang plasmonicgoldnanoislandfilmforbacterialtheranostics AT tsungrongkuo plasmonicgoldnanoislandfilmforbacterialtheranostics |