Potential Molecular Mechanisms behind the Ultra-High Dose Rate “FLASH” Effect

Potential Molecular Mechanisms behind the Ultra-High Dose Rate “FLASH” Effect

FLASH radiotherapy, or the delivery of a dose at an ultra-high dose rate (>40 Gy/s), has recently emerged as a promising tool to enhance the therapeutic index in cancer treatment. The remarkable sparing of normal tissues and equivalent tumor control by FLASH irradiation compared to conventional d...

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Bibliographic Details
Main Authors: Eva Bogaerts, Ellina Macaeva, Sofie Isebaert, Karin Haustermans
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
FLASH radiotherapy
ultra-high dose rate
radiobiology
normal tissue sparing
oxygen
immune system
Online Access:https://www.mdpi.com/1422-0067/23/20/12109

Internet

https://www.mdpi.com/1422-0067/23/20/12109

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