Sperm induction of somatic cell-cell fusion as a novel functional test
The fusion of mammalian gametes requires the interaction between IZUMO1 on the sperm and JUNO on the oocyte. We have recently shown that ectopic expression of mouse IZUMO1 induces cell-cell fusion and that sperm can fuse to fibroblasts expressing JUNO. Here, we found that the incubation of mouse spe...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/94228 |