Prenylated isoflavonoids from Fabaceae against the NorA efflux pump in Staphylococcus aureus
Abstract Overexpression of NorA efflux pumps plays a pivotal role in the multidrug-resistance mechanism in S. aureus. Here, we investigated the activities of prenylated isoflavonoids, present in the legume plant family (Fabaceae), as natural efflux pump inhibitors (EPIs) in fluoroquinolone-resistant...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-48992-8 |