Shieldin complex assembly kinetics and DNA binding by SHLD3
Within the DSB repression and resection complex Shieldin, SHLD3 binds a dimer of REV7, where the interaction with the first REV7 is the rate-limiting step in Shieldin assembly and DNA-DSB recruitment.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-04757-7 |