Aerobic exercise modulates the striatal Erk/MAPK signaling pathway and improves LID in a mouse model of Parkinson's disease

Objective: To investigate the role of the striatal extracellular signal-regulated kinase (Erk1/2) and its phosphorylation (p-Erk1/2) in aerobic training to alleviate the development of the L-DOPA induced dyskinesia (LID) in PD mice. Methods: Forty-eight male C57BL/6 N mice were randomly divided into...

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Bibliographic Details
Main Authors: Fangyuan Zhou, Longwei Wei, Yinhao Wang, Wei Chen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Brain Research Bulletin
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S036192302400039X