Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs

Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs

Intervertebral disc disease (IDD) is a debilitating spine condition that can be caused by intervertebral disc (IVD) damage which progresses towards IVD degeneration and dysfunction. Recently, human pluripotent stem cells (hPSCs) were recognized as a valuable resource for cell-based regenerative medi...

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Bibliographic Details
Main Authors: Martha E. Diaz-Hernandez, Kimihide Murakami, Shizumasa Murata, Nazir M. Khan, Sreekala P. V. Shenoy, Katrin Henke, Hiroshi Yamada, Hicham Drissi
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Cells
Subjects:
human iPSC
notochordal cells
intervertebral disc degeneration
epigenetics
bulk RNA transcriptomics
differentiation
Online Access:https://www.mdpi.com/2073-4409/13/17/1482

Internet

https://www.mdpi.com/2073-4409/13/17/1482

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