Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs

Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs

Intervertebral disc disease (IDD) is a debilitating spine condition that can be caused by intervertebral disc (IVD) damage which progresses towards IVD degeneration and dysfunction. Recently, human pluripotent stem cells (hPSCs) were recognized as a valuable resource for cell-based regenerative medi...

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Príomhchruthaitheoirí: Martha E. Diaz-Hernandez, Kimihide Murakami, Shizumasa Murata, Nazir M. Khan, Sreekala P. V. Shenoy, Katrin Henke, Hiroshi Yamada, Hicham Drissi
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: MDPI AG 2024-09-01
Sraith:Cells
Ábhair:
human iPSC
notochordal cells
intervertebral disc degeneration
epigenetics
bulk RNA transcriptomics
differentiation
Rochtain ar líne:https://www.mdpi.com/2073-4409/13/17/1482

Ar líne

https://www.mdpi.com/2073-4409/13/17/1482

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