Plasmalogen Deficiency and Overactive Fatty Acid Elongation Biomarkers in Serum of Breast Cancer Patients Pre- and Post-Surgery—New Insights on Diagnosis, Risk Assessment, and Disease Mechanisms

Plasmalogen Deficiency and Overactive Fatty Acid Elongation Biomarkers in Serum of Breast Cancer Patients Pre- and Post-Surgery—New Insights on Diagnosis, Risk Assessment, and Disease Mechanisms

The polyunsaturated fatty acid (PUFA) elongase, ELOVL5, is upregulated in breast cancer (BC) vs. adjacent normal tissue. We performed a comprehensive lipid metabolomic analysis of serum using high-resolution accurate mass spectrometry from two case-control studies that included non-BC, BC subjects p...

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Bibliographic Details
Main Authors: Satomi Tomida, Dayan B. Goodenowe, Teruhide Koyama, Etsuko Ozaki, Nagato Kuriyama, Midori Morita, Yasuyo Yamazaki, Koichi Sakaguchi, Ritei Uehara, Tetsuya Taguchi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
breast cancer
fatty acid
ELOVL5
plasmalogen
Online Access:https://www.mdpi.com/2072-6694/13/16/4170

Internet

https://www.mdpi.com/2072-6694/13/16/4170

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