An unbiased kinship estimation method for genetic data analysis

Abstract Accurate estimate of relatedness is important for genetic data analyses, such as heritability estimation and association mapping based on data collected from genome-wide association studies. Inaccurate relatedness estimates may lead to biased heritability estimations and spurious associatio...

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Bibliographic Details
Main Authors: Wei Jiang, Xiangyu Zhang, Siting Li, Shuang Song, Hongyu Zhao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-05082-2