Host range expansion of Acinetobacter phage vB_Ab4_Hep4 driven by a spontaneous tail tubular mutation

Bacteriophages (phages) represent promising alternative treatments against multidrug-resistant Acinetobacter baumannii (MDRAB) infections. The application of phages as antibacterial agents is limited by their generally narrow host ranges, so changing or expanding the host ranges of phages is benefic...

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Bibliographic Details
Main Authors: Penggang He, Feng Cao, Qianyu Qu, Huaixin Geng, Xin Yang, Tong Xu, Rui Wang, Xu Jia, Mao Lu, Peibin Zeng, Guangxin Luan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1301089/full