Neuroprotective Effects of Rhynchophylline Against Ischemic Brain Injury via Regulation of the Akt/mTOR and TLRs Signaling Pathways

Rhynchophylline (Rhy) is an alkaloid isolated from Uncaria which has long been recommended for the treatment of central nervous diseases. In our study, the neuroprotective effect of Rhy was investigated in a stroke model, namely permanent middle cerebral artery occlusion (pMCAO). Rats were injected...

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Bibliographic Details
Main Authors: Houcai Huang, Rongling Zhong, Zhi Xia, Jie Song, Liang Feng
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/8/11196