New insights into signal transduction pathways in adrenal steroidogenesis: role of mitochondrial fusion, lipid mediators, and MAPK phosphatases

New insights into signal transduction pathways in adrenal steroidogenesis: role of mitochondrial fusion, lipid mediators, and MAPK phosphatases

Hormone-receptor signal transduction has been extensively studied in adrenal gland. Zona glomerulosa and fasciculata cells are responsible for glucocorticoid and mineralocorticoid synthesis by adrenocorticotropin (ACTH) and angiotensin II (Ang II) stimulation, respectively. Since the rate-limiting s...

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Bibliographic Details
Main Authors: María Mercedes Mori Sequeiros Garcia, Cristina Paz, Ana Fernanda Castillo, Yanina Benzo, Matías A. Belluno, Ariana Balcázar Martínez, Paula Mariana Maloberti, Fabiana Cornejo Maciel, Cecilia Poderoso
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
adrenocortical cells
mitofusin 2
oxoeicosanoids
MKP-3
protein kinases
steroidogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1175677/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1175677/full

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