Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2

The Polycomb repressive complex 2 (PRC2) is a conserved chromatin-remodelling complex that catalyses the trimethylation of histone H3 lysine 27 (H3K27me3), a mark associated with gene silencing. PRC2 regulates chromatin structure and gene expression during organismal and tissue development and tissu...

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Bibliographic Details
Main Authors: Mzwanele Ngubo, Fereshteh Moradi, Caryn Y. Ito, William L. Stanford
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/10/1879