Signal processing in the TGF-beta superfamily ligand-receptor network.

The TGF-beta pathway plays a central role in tissue homeostasis and morphogenesis. It transduces a variety of extracellular signals into intracellular transcriptional responses that control a plethora of cellular processes, including cell growth, apoptosis, and differentiation. We use computational...

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Bibliographic Details
Main Authors: Jose M G Vilar, Ronald Jansen, Chris Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1356091?pdf=render