Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses

Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses

Circulating subtypes of Influenza viruses seasonally change and therefore vaccines need to be matched to these strains each year, which is why there is a need for next-generation vaccines that can elicit broad and cross-type protection. Here, Li et al. generate a human-mouse chimeric antibody with b...

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Bibliographic Details
Main Authors: Tingting Li, Junyu Chen, Qingbing Zheng, Wenhui Xue, Limin Zhang, Rui Rong, Sibo Zhang, Qian Wang, Minqing Hong, Yuyun Zhang, Lingyan Cui, Maozhou He, Zhen Lu, Zhenyong Zhang, Xin Chi, Jinjin Li, Yang Huang, Hong Wang, Jixian Tang, Dong Ying, Lizhi Zhou, Yingbin Wang, Hai Yu, Jun Zhang, Ying Gu, Yixin Chen, Shaowei Li, Ningshao Xia
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32926-5

Internet

https://doi.org/10.1038/s41467-022-32926-5

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