Clinical application of immune repertoire sequencing in solid organ transplant

Clinical application of immune repertoire sequencing in solid organ transplant

BackgroundMeasurement of T cell receptor (TCR) or B cell receptor (BCR) gene utilization may be valuable in monitoring the dynamic changes in donor-reactive clonal populations following transplantation and enabling adjustment in therapy to avoid the consequences of excess immune suppression or to pr...

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Bibliographic Details
Main Authors: Paaksum Wong, Davide P. Cina, Karen R. Sherwood, Franz Fenninger, Ruth Sapir-Pichhadze, Constantin Polychronakos, James Lan, Paul A. Keown
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
solid organ transplant
alloimmunity
lymphocyte receptor sequencing
B cell receptor (BCR)
T cell receptor (TCR)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1100479/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1100479/full

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