Interleukin-10 Conjugation to Carboxylated PVP-Coated Silver Nanoparticles for Improved Stability and Therapeutic Efficacy

Interleukin-10 Conjugation to Carboxylated PVP-Coated Silver Nanoparticles for Improved Stability and Therapeutic Efficacy

Interleukin-10 (IL-10) is a key anti-inflammatory and immunosuppressive cytokine and therefore represents a potential therapeutic agent especially in inflammatory diseases. However, despite its proven therapeutic efficacy, its short half-life and proteolytic degradation in vivo combined with its low...

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Bibliographic Details
Main Authors: Dieudonné R. Baganizi, Elijah Nyairo, Skyla A. Duncan, Shree R. Singh, Vida A. Dennis
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Nanomaterials
Subjects:
interleukin-10
poly(vinylpyrolidone) (PVP)
PVP-coated silver nanoparticles
bioconjugation
anti-inflammatory effect
storage stability
inflammatory mediators
Online Access:https://www.mdpi.com/2079-4991/7/7/165

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https://www.mdpi.com/2079-4991/7/7/165

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