Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood
DNA methylation at cytosine-phosphate-guanine (CpG) dinucleotides changes as a function of age in humans and animal models, a process that may contribute to chronic disease development. Recent studies have investigated the role of an oxidized form of DNA methylation – 5-hydroxymethylcytosine (5hmC)...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-07-01
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Series: | Epigenetics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/15592294.2018.1507198 |