Buyang Huanwu Decoction protects against STZ-induced diabetic nephropathy by inhibiting TGF-β/Smad3 signaling-mediated renal fibrosis and inflammation

Buyang Huanwu Decoction protects against STZ-induced diabetic nephropathy by inhibiting TGF-β/Smad3 signaling-mediated renal fibrosis and inflammation

Abstract Background Buyang Huanwu Decoction (BHD) is a classical Chinese Medicine formula empirically used for diabetic nephropathy (DN). However, its therapeutic efficacies and the underlying mechanisms remain obscure. In our study, we aim to evaluate the renoprotective effect of BHD on a streptozo...

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Bibliographic Details
Main Authors: Weifeng Wu, Yifan Wang, Haidi Li, Haiyong Chen, Jiangang Shen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Chinese Medicine
Subjects:
Buyang Huanwu Decoction
Calycosin-7-Glucoside
Diabetic nephropathy
Fibrosis
Inflammation
TGF-β1
Online Access:https://doi.org/10.1186/s13020-021-00531-1

Internet

https://doi.org/10.1186/s13020-021-00531-1

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