Exploring gene signatures and regulatory networks in a rat model of sciatica: implications and validation in neuropathic pain

BackgroundSciatica (neuropathic pain [NP]) is a common disease characterized by pain from radiation along the sciatic nerve. The aim of this study was to study the genes associated with chronic systolic injury of sciatic nerve (SCN-CCI) in rats by RNA-Seq technique, and to explore their potential as...

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Bibliographic Details
Main Authors: Mu Xu, Zhijian Wang, Gang Xu, Mengye Zhu, Daying Zhang, Yi Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1261217/full