TH17 Cell Frequency in Peripheral Blood Is Elevated in Overweight Children without Chronic Inflammatory Diseases

TH17 Cell Frequency in Peripheral Blood Is Elevated in Overweight Children without Chronic Inflammatory Diseases

BackgroundThe prevalence of obesity has dramatically increased in children in the last few decades and is associated with chronic inflammatory diseases. Fat tissue produces IL-6 and TNF-α, which are stimuli for TH17 cell differentiation. These cells are characterized by expression of the transcripti...

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Bibliographic Details
Main Authors: Theresa Isabell Schindler, Johanna-Josophina Wagner, Sybelle Goedicke-Fritz, Tobias Rogosch, Verena Coccejus, Verena Laudenbach, Wilfried Nikolaizik, Christoph Härtel, Rolf Felix Maier, Sebastian Kerzel, Michael Zemlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
TH17 cells
IL-17A
receptor-related orphan receptor C
inflammation
overweight
children
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01543/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01543/full

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