Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.

Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.

Ribonucleotide reductase (RNR) provides the precursors for the generation of dNTPs, which are required for DNA synthesis and repair. Here, we investigated the function of the major RNR subunits Rnr1 and Rnr3 in telomere elongation in budding yeast. We show that Rnr1 is essential for the sustained el...

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Bibliographic Details
Main Authors: André Maicher, Inbal Gazy, Sushma Sharma, Lisette Marjavaara, Gilad Grinberg, Keren Shemesh, Andrei Chabes, Martin Kupiec
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5673236?pdf=render

Internet

http://europepmc.org/articles/PMC5673236?pdf=render

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