The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever.

In humans, sexual dimorphism is associated with the presence of two X chromosomes in the female, whereas males possess only one X and a small and largely degenerate Y chromosome. How do men cope with having only a single X chromosome given that virtually all other chromosomal monosomies are lethal?...

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Bibliographic Details
Main Authors: Céline Morey, Philip Avner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3141017?pdf=render