Intrasubject subcortical quantitative referencing to boost MRI sensitivity to Parkinson's disease

Intrasubject subcortical quantitative referencing to boost MRI sensitivity to Parkinson's disease

Several postmortem studies have shown iron accumulation in the substantia nigra of Parkinson’s disease patients. Iron concentration can be estimated via MRI-R2∗ mapping. To assess the changes in R2∗ occurring in Parkinson’s disease patients compared to controls, a multicentre transversal study was c...

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Main Authors: Laila Khedher, Jean-Marie Bonny, Ana Marques, Elodie Durand, Bruno Pereira, Marie Chupin, Tiphaine Vidal, Carine Chassain, Luc Defebvre, Nicolas Carriere, Valerie Fraix, Elena Moro, Stéphane Thobois, Elise Metereau, Graziella Mangone, Marie Vidailhet, Jean-Christophe Corvol, Stéphane Lehéricy, Nicolas Menjot de Champfleur, Christian Geny, Umberto Spampinato, Wassilios Meissner, Solène Frismand, Emmanuelle Schmitt, Anne Doé de Maindreville, Christophe Portefaix, Philippe Remy, Gilles Fénelon, Jean Luc Houeto, Olivier Colin, Olivier Rascol, Patrice Peran, Franck Durif
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Parkinson’s disease
Magnetic resonance imaging
Variability
Iron
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222002960

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http://www.sciencedirect.com/science/article/pii/S2213158222002960

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