The cell autonomous and non-autonomous roles of itaconate in immune response

Itaconate which is discovered as a mammalian metabolite possessing antimicrobial and immunoregulatory activity has attracted much attention in the field of immunometabolism. Itaconate is synthesized by myeloid cells under conditions of pathogen infection and sterile inflammation. In addition to regu...

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Bibliographic Details
Main Authors: Chao Chen, Xinjian Li
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Insight
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772892724000798