The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells—Lessons Learned from Different Transgenic Mouse Models

Regulatory T cells (Treg) are essential for the maintenance of peripheral tolerance. Treg dysfunction results in diverse inflammatory and autoimmune diseases with life-threatening consequences. β<sub>2</sub>-integrins (CD11a-d/CD18) play important roles in the migration of leukocytes int...

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Bibliographic Details
Main Authors: Tanja Klaus, Alicia Wilson, Michael Fichter, Matthias Bros, Tobias Bopp, Stephan Grabbe
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/7/6331