One-Step Automatic Radiosynthesis and Evaluation of [<sup>18</sup>F]TM-30089 as GPR44 Radiotracer

One-Step Automatic Radiosynthesis and Evaluation of [<sup>18</sup>F]TM-30089 as GPR44 Radiotracer

Recently, a G-protein coupled receptor 44 (GPR44) was discovered to play a significant role in the process of inflammation-related diseases, including cancer and diabetes. However, the precise role of GPR44 has yet to be fully elucidated. Currently, there is a strong and urgent need for the developm...

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Bibliographic Details
Main Authors: Jiangling Peng, Wei Tang, Jeffrey Rawson, Lynn Miao, Nelson Gonzalez, Runkai Yin, Jiaqi Chen, Melinda Ji, Zhixuan Li, Anna Gao, Andy Z. Wu, John E. Shively, Fouad Kandeel, Junfeng Li
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
G protein-coupled receptor 44 (GPR44)
<sup>18</sup>F-labeling
chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2)
prostaglandin D<sub>2</sub> receptor 2 (DP2)
prostaglandin D<sub>2</sub> (PGD<sub>2</sub>)
inflammation
Online Access:https://www.mdpi.com/1424-8247/16/10/1480

Internet

https://www.mdpi.com/1424-8247/16/10/1480

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