Multiple time-series expression trajectories imply dynamic functional changes during cellular senescence

Cellular senescence is a dynamic process driven by epigenetic and genetic changes. Although some transcriptomic signatures of senescent cells have been discovered, how these senescence-related signals change over time remains largely unclear. Here, we profiled the transcriptome dynamics of human der...

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Bibliographic Details
Main Authors: Ming-Xia Ge, Qin Yu, Gong-Hua Li, Li-Qin Yang, Yonghan He, Ji Li, Qing-Peng Kong
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003415