TcdB of <i>Clostridioides difficile</i> Mediates RAS-Dependent Necrosis in Epithelial Cells
A <i>Clostridioides difficile</i> infection (CDI) is the most common nosocomial infection worldwide. The main virulence factors of pathogenic <i>C. difficile</i> are TcdA and TcdB, which inhibit small Rho-GTPases. The inhibition of small Rho-GTPases leads to the so-called cyt...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/8/4258 |