Expanding the epitranscriptome: Dihydrouridine in mRNA.

Nucleotide modifications can markedly influence mRNA processing and metabolism. New studies, one in PLOS Biology, show that approximately 130 yeast mRNAs contain dihydrouridine, a derivative of uridine. Functional studies show that dihydrouridine, in some cases, can affect mRNA splicing.

Bibliographic Details
Main Authors: Sameer Dixit, Samie R Jaffrey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001720