Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

Abstract Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark of autophagy is the formation of a phagophore that engulfs cytosolic materials for degradation and recycling to synthesize essential components. Basal autophagy is constitutively active under normal con...

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Bibliographic Details
Main Authors: Su Min Lim, Ezanee Azlina Mohamad Hanif, Siok-Fong Chin
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00570-z