Bioanalytical method validation, biopharmaceutical and pharmacokinetic evaluation of GSK-650394, a serum- and glucocorticoid-regulated kinase 1 inhibitor

GSK-650394 is an inhibitor of serum- and glucocorticoid-regulated kinase 1 that displays potency for treating cancer, hypertension, cardiovascular and neuronal diseases, such as Parkinson’s disease. However, the biopharmaceutical properties and pharmacokinetics of GSK-650394 have not been studied ex...

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Bibliographic Details
Main Authors: Qui-Dong Le, Van-An Duong, Sang-Hun Lee, Thi-Thao-Linh Nguyen, Han-Joo Maeng
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522200778X