A CUG codon-adapted anchor-away toolkit for functional analysis of genes in Candida albicans

A CUG codon-adapted anchor-away toolkit for functional analysis of genes in Candida albicans

ABSTRACTPromoter shutoff of essential genes in the diploid Candida albicans has often been insufficient to create tight, conditional null alleles due to leaky expression and has been a stumbling block in pathogenesis research. Moreover, homozygous deletion of non-essential genes has often been probl...

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Bibliographic Details
Main Authors: Basharat Bashir Teli, Priyanka Nagar, Yumnam Priyadarshini, Poonam Poonia, Krishnamurthy Natarajan
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mSphere
Subjects:
Candida albicans
functional genomics
anchor-away
essential genes
non-essential genes
TBP1
Online Access:https://journals.asm.org/doi/10.1128/msphere.00703-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00703-23

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