Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers

Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers

Abstract Background Identification of biomarkers of cigarette smoke –induced lung damage and early COPD is an area of intense interest. Glucose regulated protein of 78 kD (i.e., GRP78), a multi-functional protein which mediates cell responses to oxidant stress, is increased in the lungs of cigarette...

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Bibliographic Details
Main Authors: Mark O. Aksoy, Victor Kim, William D. Cornwell, Thomas J. Rogers, Beata Kosmider, Karim Bahmed, Carlos Barrero, Salim Merali, Neena Shetty, Steven G. Kelsen
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Respiratory Research
Subjects:
Oxidant stress
GRP78
Cigarette smoke
COPD
Histone deacetylase
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12931-017-0561-6

Internet

http://link.springer.com/article/10.1186/s12931-017-0561-6

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