Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria

Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria

Abstract Cerebral malaria (CM), the most lethal complication of Plasmodium falciparum severe malaria (SM), remains fatal for 15–25% of affected children despite the availability of treatment. P. falciparum infects and multiplies in erythrocytes, contributing to anemia, parasite sequestration, and in...

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Bibliographic Details
Main Authors: Jeremy Fraering, Virginie Salnot, Emilie-Fleur Gautier, Sem Ezinmegnon, Nicolas Argy, Katell Peoc’h, Hana Manceau, Jules Alao, François Guillonneau, Florence Migot-Nabias, Gwladys I Bertin, Claire Kamaliddin, NeuroCM consortium
Format: Article
Language:English
Published: Springer Nature 2024-01-01
Series:EMBO Molecular Medicine
Subjects:
Cerebral Malaria
LC-MS/MS
Plasmodium falciparum
Biomarkers
Red Blood Cells
Online Access:https://doi.org/10.1038/s44321-023-00010-0

Internet

https://doi.org/10.1038/s44321-023-00010-0

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