Circulating Extracellular Vesicles and Particles Derived From Adipocytes: The Potential Role in Spreading MicroRNAs Associated With Cellular Senescence

Circulating Extracellular Vesicles and Particles Derived From Adipocytes: The Potential Role in Spreading MicroRNAs Associated With Cellular Senescence

Aging is associated with adipose tissue dysfunction and is recognized as a risk factor for shortened life span. Considering that in vitro findings have shown the involvement of microRNA in extracellular vesicles and particles (EVPs) on senescence, we hypothesized that circulating EVPs derived from a...

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Bibliographic Details
Main Authors: Ionara Rodrigues Siqueira, Andressa de Souza Rodrigues, Marina Siqueira Flores, Eduarda Letícia Vieira Cunha, Madeleine Goldberg, Brennan Harmon, Rachael Batabyal, Robert J. Freishtat, Laura Reck Cechinel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Aging
Subjects:
adipocyte-derived exosomes
microRNA
cellular senescence
aging
obesity
adipose tissue dysfunctions
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.867100/full

Internet

https://www.frontiersin.org/articles/10.3389/fragi.2022.867100/full

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