DMF Activates NRF2 to Inhibit the Pro-Invasion Ability of TAMs in Breast Cancer

Tumor-associated macrophages (TAMs) account for more than 50% of the cells in the tumor immune microenvironment of patients with breast cancer. A high TAM density is associated with a poor clinical prognosis. Targeting TAMs is a promising therapeutic strategy because they promote tumor growth, devel...

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Bibliographic Details
Main Authors: Ying Li, Yaxu Jia, Yurong Xu, Kan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.706448/full