GPIbα is the driving force of hepatic thrombopoietin generation
Abstract Thrombopoietin (TPO), a glycoprotein hormone produced predominantly in the liver, plays important roles in the hematopoietic stem cell (HSC) niche, and is essential for megakaryopoiesis and platelet generation. Long‐standing understanding proposes that TPO is constitutively produced by hepa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | Research and Practice in Thrombosis and Haemostasis |
Subjects: | |
Online Access: | https://doi.org/10.1002/rth2.12506 |