Mechanisms of tissue degeneration mediated by periostin in spinal degenerative diseases and their implications for pathology and diagnosis: a review

Mechanisms of tissue degeneration mediated by periostin in spinal degenerative diseases and their implications for pathology and diagnosis: a review

Periostin (POSTN) serves a dual role as both a matricellular protein and an extracellular matrix (ECM) protein and is widely expressed in various tissues and cells. As an ECM protein, POSTN binds to integrin receptors, transduces signals to cells, enabling cell activation. POSTN has been linked with...

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Bibliographic Details
Main Authors: Tomohito Yoshihara, Tadatsugu Morimoto, Hirohito Hirata, Masatoshi Murayama, Toshihiro Nonaka, Masatsugu Tsukamoto, Yu Toda, Takaomi Kobayashi, Kenji Izuhara, Masaaki Mawatari
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Medicine
Subjects:
periostin
pathway
biomarker
mechanical stress
inflammation
spinal degenerative diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1276900/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1276900/full

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