Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Tauopathies are neurodegenerative disorders involving the accumulation of tau isoforms in cell subpopulations such as astrocytes. The origins of the 3R and 4R isoforms of tau that accumulate in astrocytes remain unclear. Extracellular vesicles (EVs) were isolated from primary neurons overexpressing...

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Bibliographic Details
Main Authors: Romain Perbet, Valentin Zufferey, Elodie Leroux, Enea Parietti, Jeanne Espourteille, Lucas Culebras, Sylvain Perriot, Renaud Du Pasquier, Séverine Bégard, Vincent Deramecourt, Nicole Déglon, Nicolas Toni, Luc Buée, Morvane Colin, Kevin Richetin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
tauopathies
tau spreading
extracellular vesicles
astrocytes
mitochondria
Online Access:https://www.mdpi.com/2073-4409/12/7/985

Internet

https://www.mdpi.com/2073-4409/12/7/985

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