Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System

Nucleotide excision repair (NER) is an essential DNA repair system distinguished from other such systems by its extraordinary versatility. NER removes a wide variety of structurally dissimilar lesions having only their bulkiness in common. NER can also repair several less bulky nucleobase lesions, s...

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Bibliographic Details
Main Authors: Seung-Joo Lee, Rou-Jia Sung, Gregory L. Verdine
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2019-01-01
Series:Research
Online Access:http://dx.doi.org/10.34133/2019/5641746