C3a-C3aR signaling is a novel modulator of skeletal homeostasis

Osteoimmune studies have identified complement signaling as an important regulator of the skeleton. Specifically, complement anaphylatoxin receptors (i.e., C3aR, C5aR) are expressed on osteoblasts and osteoclasts, implying that C3a and/or C5a may be candidate mediators of skeletal homeostasis. The s...

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Bibliographic Details
Main Authors: Megan B. Kuhn, Hayden S. VandenBerg, Andrew J. Reynolds, Matthew D. Carson, Amy J. Warner, Amanda C. LaRue, Chad M. Novince, Jessica D. Hathaway-Schrader
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000104