Fabrication and intracellular delivery of doxorubicin/carbonate apatite nanocomposites: effect on growth retardation of established colon tumor.

In continuing search for effective treatments of cancer, the emerging model aims at efficient intracellular delivery of therapeutics into tumor cells in order to increase the drug concentration. However, the implementation of this strategy suffers from inefficient cellular uptake and drug resistance...

Full description

Bibliographic Details
Main Authors: Sharif Hossain, Hirofumi Yamamoto, Ezharul Hoque Chowdhury, Xin Wu, Hajime Hirose, Amranul Haque, Yuichiro Doki, Masaki Mori, Toshihiro Akaike
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3629059?pdf=render