Combined Effects of Methyldopa and Baicalein or <i>Scutellaria baicalensis</i> Roots Extract on Blood Pressure, Heart Rate, and Expression of Inflammatory and Vascular Disease-Related Factors in Spontaneously Hypertensive Pregnant Rats

Combined Effects of Methyldopa and Baicalein or <i>Scutellaria baicalensis</i> Roots Extract on Blood Pressure, Heart Rate, and Expression of Inflammatory and Vascular Disease-Related Factors in Spontaneously Hypertensive Pregnant Rats

The aim of the study was to investigate the effect of baicalein or <i>Scutellaria baicalensis</i> root extract interaction with methyldopa in pregnant spontaneously hypertensive rats (SHR) at the pharmacodynamic, molecular, and biochemical levels. The rats, after confirming pregnancy, re...

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Bibliographic Details
Main Authors: Michał Szulc, Radosław Kujawski, Przemysław Ł. Mikołajczak, Anna Bogacz, Marlena Wolek, Aleksandra Górska, Kamila Czora-Poczwardowska, Marcin Ożarowski, Agnieszka Gryszczyńska, Justyna Baraniak, Małgorzata Kania-Dobrowolska, Artur Adamczak, Ewa Iwańczyk-Skalska, Paweł P. Jagodziński, Bogusław Czerny, Adam Kamiński, Izabela Uzar, Agnieszka Seremak-Mrozikiewicz
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
placenta
<i>Scutellaria baicalensis</i>
baicalein
methyldopa
blood pressure
mRNA expression
Online Access:https://www.mdpi.com/1424-8247/15/11/1342

Internet

https://www.mdpi.com/1424-8247/15/11/1342

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